Thank you for this nuanced perspective to healthy weight loss, Dr Brown. I struggled with the metabolic issues in my younger years so in hindsight your points deeply resonated with me. For me elevated cortisol and insulin hormones caused by unhealthy lifestyle choices were the culprit. The biggest contributor for me to reverse my prediabetes and abdominal obesity was improving sleep, fixing my nutrition like eating more protein with moderate healthy fats with less refined carbs, and staying active in a smart way. One key takeaway for me is the impact of those medications which I did not use but many people do. You inspired me to write a story about it reflecting my research. I hope this story finds many readers as it can change their lives positively.