Thank you for sharing your experience and research on this important health topic. I don't intend to be judgmental but the root cause seems to be looking for happiness in external sources and trying to numb our painful emotions which require acceptance, expression, and proper management despite their painful effects. Of course each person has their own challenges and we never know the exact reason for them. I have huge empathy and compassion for those people as I know how difficult it could be to deal with addictions when the neural pathways got very thick and deltafosb level go beyond the manageable state over time.