Hi Olive as documented in the literature in general hydrophilic statins like pravastatin or rosuvastatin may cause less muscular events than lipophilic statins simvastatin or atorvastatin due to lower passive diffusion into muscle cells. Cardiologist also changed to a hydrophilic one for my relative. It is based on trial and error. I talk with many people in my circles and they all have different reactions to different types. You inspired me to share my research. There was a significant meta-analysis by the Lancet reviewing all clinical trials which summarized all the paper I read about it. I will summarize it soon.