Great question. I tried to explain it but obviously it was not clear. There is a well-documented causal relationship between dopamine dysregulation and Parkinson's disease in the literature. Parkinson's disease is characterized by the degeneration of dopamine-producing neurons in certain regions in the brain like the substantia nigra. This loss of dopamine-producing cells leads to a significant reduction in dopamine levels in the brain, which results in the motor symptoms associated with Parkinson's disease, such as tremors, rigidity, and bradykinesia (slowed movement). The link between dopamine dysregulation and Parkinson's disease is further supported by the effectiveness of dopamine replacement therapy (DRT) in managing the symptoms of Parkinson's disease as I explained in a separate section. Thank you for reading and commenting.